Use of Sera from Humans and Dolphins with Lacaziosis and Sera from Experimentally Infected Mice for Western Blot Analyses of Lacazia loboi Antigens-Reference-Cited by-同舟云学术

Use of Sera from Humans and Dolphins with Lacaziosis and Sera from Experimentally Infected Mice for Western Blot Analyses of Lacazia loboi Antigens

Published:2008-01 Issue:1 Volume:15 Page:164-167
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Mendoza Leonel¹²³⁴⁵,Belone Andréa F. F.¹²³⁴⁵,Vilela Raquel¹²³⁴⁵,Rehtanz Manuela¹²³⁴⁵,Bossart Gregory D.¹²³⁴⁵,Reif John S.¹²³⁴⁵,Fair Patricia A.¹²³⁴⁵,Durden Wendy N.¹²³⁴⁵,St. Leger Judy¹²³⁴⁵,Travassos Luiz R.¹²³⁴⁵,Rosa Patricia S.¹²³⁴⁵

Affiliation:

1. Biomedical Laboratory Diagnostics Program, Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan 48824-1031

2. Instituto Lauro de Souza Lima, Bauru, São Paulo, Brazil

3. New York University, Department of Basic Sciences, Infectious Diseases, New York, New York 10010

4. Harbor Branch Oceanographic Institution, Center for Coastal Research, Marine Mammal Research and Conservation, Fort Pierce, Florida 34946

5. Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado 80523

Abstract

ABSTRACT Antibodies in the sera of patients with lacaziosis recognized an ∼193-kDa antigen and other Lacazia loboi antigens. Paracoccidioides brasiliensis gp43 antigen was detected by all evaluated sera, but they failed to detect a protein with the same molecular mass in L. loboi extracts. This study is the first to examine the humoral response to L. loboi antigens by using multiple host sera.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00201-07

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