Affiliation:
1. Department of Pathology, University of New Mexico Health Science Center, Albuquerque, USA.
Abstract
The complete M segment sequences of hantaviruses amplified from tissues of a patient with hantavirus pulmonary syndrome in the northeastern United States and from white-footed mice, Peromyscus leucopus, from New York were 99% identical and differed from those of Four Corners virus by 23%. The serum of this patient failed to recognize a conserved, immunodominant epitope of the Four Corners virus G1 glycoprotein. Collectively, these findings indicate that P. leucopus harbors a genetically and antigenically distinct hantavirus that causes hantavirus pulmonary syndrome.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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