Susceptibility and signs associated with mouse adenovirus type 1 infection of adult outbred Swiss mice

Abstract

Adult Swiss outbred mice from two sources had a nearly 6,000-fold difference in susceptibility to mouse adenovirus type 1-induced disease. This difference was not attributable to differential organ tropism. Signs associated with mouse adenovirus type 1 infection that have not been previously reported are described at the clinical, gross pathological, and histological levels.