Abstract
Taurocholate, desoxycholate, and cholate stimulated germination of Clostridium difficile spores in broth medium and enhanced recovery of C. difficile spores on a selective agar medium. Desoxycholate and some crude taurocholate preparations also inhibited multiplication of vegetative cells. At a concentration of 1.2 X 10(-2) M, sodium cholate inhibited multiplication of vegetative cells, but at concentrations of 1.2 X 10(-3) to 2.4 X 10(-3) M, it stimulated germination without inhibiting cell multiplication. Thus, pure sodium taurocholate and sodium cholate may effectively be incorporated in cefoxitin-cycloserine-fructose agar, whereas some crude preparations of sodium taurocholate decrease recovery on this medium.
Publisher
American Society for Microbiology
Reference7 articles.
1. Drasar B. S. and M. J. Hill. 1974. Human intestinal flora. Academic Press Inc. New York.
2. Selective and differential medium for isolation of Clostridium difficile;George W. C.;J. Clin. Microbiol.,1979
3. Gould G. W. 1971. Methods for studying bacterial spores. In J. R. Norris and D. W. Ribbons (ed.) Methods in microbiology. Academic Press Inc. New York.
4. Epidemiology of enterocolitis due to Clostridium difficile;Larson H. E.;J. Infect. Dis.,1980
5. Le taurocholate de sodium, facteur de germination in vitro et in vivo, dans le tube digestif d'animaux "gnotoxeniques;Raibaud P.;Ann. Microbiol.,1974
Cited by
165 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献