mar Operon Involved in Multidrug Resistance of Enterobacter aerogenes-Reference-Cited by-同舟云学术

mar Operon Involved in Multidrug Resistance of Enterobacter aerogenes

Published:2002-04 Issue:4 Volume:46 Page:1093-1097
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Chollet Renaud¹,Bollet Claude¹,Chevalier Jacqueline¹,Malléa Monique¹,Pagès Jean-Marie¹,Davin-Regli Anne¹

Affiliation:

1. Enveloppe Bactérienne, Antibiotiques et Colonisation, CJF 9606-EA 2197, Facultés de Médecine et Pharmacie, Université de la Méditerranée, 13385 Marseille Cedex 05, France

Abstract

ABSTRACT We determined the sequence of the entire marRAB operon in Enterobacter aerogenes . It is functionally and structurally analogous to the Escherichia coli operon. The overexpression of E. aerogenes MarA induces a multidrug resistance phenotype in a susceptible strain, demonstrated by a noticeable resistance to various antibiotics, a decrease in immunodetected porins, and active efflux of norfloxacin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.4.1093-1097.2002

Reference24 articles.

1. Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon

2. Alekshun, M. N., Y. S. Kim, and S. B. Levy. 2000. Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding. Mol. Microbiol.35:1394-1404.

3. Ausubel F. M. R. E. Brent D. D. Kingston J. G. Moore J. A. Seidman and K. Struhl. 1995. Current protocols in molecular biology. John Wiley & Sons New York N.Y.

4. Differential Expression of over 60 Chromosomal Genes in Escherichia coli by Constitutive Expression of MarA

5. Imipenem Resistance of Enterobacter aerogenes Mediated by Outer Membrane Permeability

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