Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains-Reference-Cited by-同舟云学术

Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains

Published:2002-04 Issue:4 Volume:46 Page:1147-1152
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ma Xiao Xue¹,Ito Teruyo¹,Tiensasitorn Chuntima¹,Jamklang Mantana¹,Chongtrakool Piriyaporn¹,Boyle-Vavra Susan²,Daum Robert S.²,Hiramatsu Keiichi¹

Affiliation:

1. Department of Bacteriology, Juntendo University, Tokyo, Japan

2. Department of Pediatrics, University of Chicago Children's Hospital, Chicago, Illinois

Abstract

ABSTRACT We identified a new type of staphylococcal cassette chromosome mec (SCC mec ) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCC mec , had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCC mec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-β-lactam antibiotics, the type IV SCC mec was devoid of any antibiotic resistance genes other than the mecA gene.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.4.1147-1152.2002

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