Unexpected Mechanism of Biodegradation and Defluorination of 2,2-Difluoro-1,3-Benzodioxole by Pseudomonas putida F1-Reference-Cited by-同舟云学术

Unexpected Mechanism of Biodegradation and Defluorination of 2,2-Difluoro-1,3-Benzodioxole by Pseudomonas putida F1

Published:2021-12-21 Issue:6 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Bygd Madison D.¹^ORCID,Aukema Kelly G.²³^ORCID,Richman Jack E.²³,Wackett Lawrence P.²³^ORCID

Affiliation:

1. Microbial Engineering, University of Minnesota, St. Paul, Minnesota, USA

2. Biochemistry, Molecular Biology and Biophysics, University of Minnesota, St. Paul, Minnesota, USA

3. BioTechnology Institute, University of Minnesota, St. Paul, Minnesota, USA

Abstract

There are more than 9,000 polyfluorinated compounds developed for commercial use, some negatively impacting human health, and they are generally considered to be resistant to biodegradation. Only a limited number of studies have identified microbes with enzymes sufficiently reactive to defluorinate difluoromethylene carbon groups.

Funder

MnDRIVE Industry and the Environment

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.03001-21

Reference57 articles.

1. A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects

2. Fluorinated Organics in the Biosphere

3. The fluorinated natural products