Affiliation:
1. Arbovirology Section, Center for Disease Control, Atlanta, Georgia 30333
Abstract
Mice, guinea pigs, and duck embryo cell cultures were inoculated with known subtypes of Venezuelan equine encephalomyelitis (VEE) virus and the attenuated (TC-83) strain of VEE. With the exception of TC-83, all strains were highly pathogenic for suckling mice by either intracranial or intraperitoneal routes of inoculation used. Virulence for older mice and guinea pigs provided a means to distinguish strains. In addition, virulence or lack of virulence for adult mice or guinea pigs provides a rapid method for separating epizootic subtype IB from TC-83 VEE virus isolates.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference9 articles.
1. Order of Magnitude;Haldane J. B. S.;Nature (London),1960
2. Experimental infection of horses with three strains of Venezuelan equine encephalomyelitis virus. I. Clinical and virological studies;Henderson B. E.;Amer. J. Epidemiol.,1971
3. McKinney R. W. 1972. Inactivated and live VEE vaccines-a review p. 369-376. In Venezuelan encephalitis. Proceedings of the workshop-symposium on Venezuelan encephalitis virus. Pan American Health Organization scientific publication no. 243. Pan American Health Organization Washington D.C.
4. Isolation of the vaccine strain of Venezuelan equine encephalomyelitis virus from mosquitoes;Pedersen C. E.;Louisiana. Amer. J. Epidemiol.,1972
5. Comparative studies of plaque variants derived from a Florida strain of Venezuelan equine encephalomyelitis virus;Pedersen C. E.;Infect. Immunity,1972
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