Affiliation:
1. Department of Biochemistry, Faculty of Medicine, University of Singapore, Singapore 3
Abstract
Long-chain saturated fatty acids (C
13
to C
18
) and fatty alcohols (C
12
to C
18
) were well utilized by three different soil isolates of
Cladosporium resinae
as the sole carbon and energy sources in static liquid cultures. Shorter-chain compounds, down to C
5
, did not support growth and were in fact toxic towards the fungus growing on glucose. Rapid and considerable potassium efflux, protein leakage, and inhibition of endogenous respiration were observed in the presence of the shorter fatty acids and alcohols. Possible mechanisms and significance of the toxicity are discussed.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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