Complete Genome Sequence of Streptomyces cattleya NRRL 8057, a Producer of Antibiotics and Fluorometabolites

Author:

Barbe Valérie1,Bouzon Madeleine1,Mangenot Sophie1,Badet Bernard2,Poulain Julie1,Segurens Béatrice13,Vallenet David13,Marlière Philippe4,Weissenbach Jean13

Affiliation:

1. CEA, DSV, IG, Genoscope, 2 rue Gaston Crémieux, CP5706, F-91057 Evry Cedex, France

2. ICSN-UPR2301, Laboratoire de Chimie Biologique, 91198 Gif-sur-Yvette Cedex, France

3. CNRS UMR 8030, Université d'Evry, CEA, DSV, IG, Genoscope, 2 rue Gaston Crémieux, CP5706, F-91057 Evry Cedex, France

4. Isthmus SARL, Paris, France

Abstract

ABSTRACT Streptomyces cattleya , a producer of the antibiotics thienamycin and cephamycin C, is one of the rare bacteria known to synthesize fluorinated metabolites. The genome consists of two linear replicons. The genes involved in fluorine metabolism and in the biosynthesis of the antibiotic thienamycin were mapped on both replicons.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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