The global regulator CsrA of Escherichia coli is a specific mRNA-binding protein-Reference-Cited by-同舟云学术

The global regulator CsrA of Escherichia coli is a specific mRNA-binding protein

Published:1997-07 Issue:14 Volume:179 Page:4639-4642
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Liu M Y¹,Romeo T¹

Affiliation:

1. Department of Microbiology and Immunology, University of North Texas Health Science Center at Fort Worth, 76107-2699, USA.

Abstract

The csrA gene encodes a global regulatory protein which facilitates glgC mRNA decay in vivo. A purified recombinant CsrA protein was found to inhibit in vitro glg (glycogen biosynthesis) gene expression posttranscriptionally and bind specifically to a glgC runoff transcript without causing its decay. Our results provide further insight into the mechanism by which CsrA functions as an mRNA decay factor.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.179.14.4639-4642.1997

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