Evidence for a phosphorylation site in cytomegalovirus glycoprotein gB

Author:

Norais N1,Hall J A1,Gross L1,Tang D1,Kaur S1,Chamberlain S H1,Burke R L1,Marcus F1

Affiliation:

1. Chiron Corporation, Emeryville, California 94608, USA.

Abstract

As part of our vaccine program, we have purified a recombinant form of human cytomegalovirus glycoprotein B that is able to induce high titers of virus-neutralizing antibodies. The isolated protein was found to be phosphorylated at a serine residue in position -7 from the C terminus of the protein. The corresponding synthetic peptide, HLKDSDEEENV, was an efficient in vitro substrate of casein kinase II.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference23 articles.

1. Alder S. P. Infectious agents and disease in press.

2. Allen G. 1981. Sequencing of proteins and peptides p. 53. Elsevier Amsterdam.

3. Allende J. E. Personal communication.

4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation;Allende J. E.;FASEB J.,1995

5. Nomenclature for peptide fragment ions (positive ions);Biemann K.;Methods Enzymol.,1990

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3