Novel Complex sul1 -Type Integron in Escherichia coli Carrying bla CTX-M-9

Author:

Sabaté Montserrat1,Navarro Ferran1,Miró Elisenda1,Campoy Susana2,Mirelis Beatriz1,Barbé Jordi23,Prats Guillem1

Affiliation:

1. Departament de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma, 08025 Barcelona

2. Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona

3. Centre de Recerca en Sanitat Animal (CreSA), 08193 Bellaterra, Spain

Abstract

ABSTRACT For the present report, a novel complex class 1 integron, In60, was characterized. Part of this integron includes the bla CTX-M-9 gene and its downstream nucleotide sequence, which shares 81% and 78% nucleotide identity with those of kluA-1 β-lactamase and orf3 of K. ascorbata , respectively. Furthermore, a new insertion sequence, IS 3000 , has been found in In60. PCR analysis indicates that integron In60 is present in 33 of 34 nonclonal enterobacterial isolates carrying the putative β-lactamase CTX-M-9.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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