Affiliation:
1. Department of Microbiology, University of Georgia, Athens, Georgia, USA
Abstract
2-aminoacrylate (2AA) is a reactive metabolite formed as an intermediate in various enzymatic reactions. In the absence of RidA, this metabolite can persist
in vivo
where it attacks and inactivates specific PLP-dependent enzymes, causing metabolic defects and organism-specific phenotypes.
Funder
HHS | National Institutes of Health
Publisher
American Society for Microbiology
Cited by
5 articles.
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