The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway-Reference-Cited by-同舟云学术

The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway

Published:2021-10-26 Issue:5 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Wang Ling¹²^ORCID,Howell Mary E. A.¹,Sparks-Wallace Ayrianna¹,Zhao Juan¹²,Hensley Culton R.¹,Nicksic Camri A.¹,Horne Shanna R.¹,Mohr Kaylea B.¹,Moorman Jonathan P.¹²³,Yao Zhi Q.¹²³^ORCID,Ning Shunbin¹²^ORCID

Affiliation:

1. Department of Internal Medicine, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, USA

2. Center of Excellence for Inflammation, Infectious Diseases and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, USA

3. HCV/HIV Program, James H Quillen VA Medical Center, Johnson City, Tennessee, USA

Abstract

As a ubiquitin sensor and a signal-transducing adaptor, p62 is crucial for NF-κB activation, which involves the ubiquitin machinery in diverse contexts. However, whether p62 is required for EBV LMP1 activation of NF-κB is an open question.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.01097-21

Reference74 articles.

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