Activities of Nigerian chewing stick extracts against Bacteroides gingivalis and Bacteroides melaninogenicus

Author:

Rotimi V O1,Laughon B E1,Bartlett J G1,Mosadomi H A1

Affiliation:

1. Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

Abstract

The in vitro activities of extracts of Nigerian chewing sticks against Bacteroides gingivalis and B. melaninogenicus are presented. The greatest inhibitory action was produced by Serindeia werneckei, whereas Fagara zanthoxyloides produced no appreciable inhibitory effect. A generally good correlation was found between the killing curves and MICs. Only extracts of Anogeissus leiocarpus showed acute toxicity in mice.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference15 articles.

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2. Native cures in Nigeria: II. The antimicrobial properties of buffered extracts of chewing sticks;El-Said R.;Lloydia,1971

3. The chewing sticks in oral health care;Enwonwu C. O.;World Health Forum,1985

4. Extracts of Fagara zanthoxyloides root in sickle cell anaemia: toxicology and preliminary clinical trials;Isaacs-Sodeye W. A.;Acta Haematol.,1975

5. The predominant cultivable flora of tooth surface plaque removed from institutional subjects;Loesche W. J.;Arch. Oral Biol.,1972

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