Genetic Diversity of Plasmodium falciparum and Distribution of Antimalarial Drug Resistance Mutations in Symptomatic and Asymptomatic Infections-Reference-Cited by-同舟云学术

Genetic Diversity of Plasmodium falciparum and Distribution of Antimalarial Drug Resistance Mutations in Symptomatic and Asymptomatic Infections

Published:2022-08-16 Issue:8 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Sarah-Matio Elangwe M.¹²,Guillochon Emilie³,Nsango Sandrine E.²⁴,Abate Luc¹,Ngou Christelle M.¹²,Bouopda Gaelle A.²⁴,Feufack-Donfack Lionel B.²,Bayibéki Albert N.⁵,Tchioffo Tsapi Majoline¹,Talman Arthur¹,Marin-Menendez Alejandro¹,Ayong Lawrence²,Claessens Antoine¹⁶,Lefèvre Thierry¹,Berry Antoine⁷⁸^ORCID,Morlais Isabelle¹^ORCID

Affiliation:

1. MIVEGEC, Université de Montpellier, CNRS, IRD, Montpellier, France

2. Malaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon

3. Université de Paris, MERIT, IRD, Paris, France

4. Department of Biological Sciences, Faculté de Médecine et des Sciences Pharmaceutiques, Université de Douala, Douala, Cameroon

5. Université Catholique d’Afrique Centrale, Yaoundé, Cameroon

6. LPHI, Université de Montpellier, INSERM, CNRS, Montpellier, France

7. Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse, CNRS UMR5051, INSERM UMR1291, UPS, Toulouse, France

8. Service de Parasitologie_Mycologie, Centre Hospitalier Universitaire de Toulouse, Toulouse, France

Abstract

Malaria control relies on passive case detection, and this strategy fails detecting asymptomatic infections. In addition, infections in endemic areas harbor multiple parasite genotypes that could affect case management and malaria epidemiology.

Funder

Agence Nationale de la Recherche

Institut de Recherche pour le Développement

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00188-22

Reference55 articles.

1. Asymptomatic malaria infections: detectability, transmissibility and public health relevance

2. Treatment and prevention of malaria in children