Comparison of the Directigen Flu A+B Membrane Enzyme Immunoassay with Viral Culture for Rapid Detection of Influenza A and B Viruses in Respiratory Specimens-Reference-Cited by-同舟云学术

Comparison of the Directigen Flu A+B Membrane Enzyme Immunoassay with Viral Culture for Rapid Detection of Influenza A and B Viruses in Respiratory Specimens

Published:2004-08 Issue:8 Volume:42 Page:3707-3710
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Cazacu Andreea C.¹,Chung Sooyoung E.²,Greer Jewel¹³,Demmler Gail J.¹³

Affiliation:

1. Department of Pediatrics, Baylor College of Medicine

2. New York University School of Medicine, New York, New York 10016

3. Diagnostic Virology Laboratory, Texas Children's Hospital, Houston, Texas 77030

Abstract

ABSTRACT The performance of a commercially available, rapid membrane enzyme immunoassay for influenza A and B virus detection was compared to that of viral culture in 4,092 respiratory specimens collected from patients presenting with respiratory symptoms during the 2002-2003 influenza season. The test's overall sensitivity was 43.83%, lower than previously reported but similar for detection of both influenza A and B viruses (42.98 versus 44.76%). However, specificity, 99.74%, was excellent for both influenza A and B viruses (99.82 versus 99.92%). These values make this test a very good confirmatory test when clinical suspicion is high, but a less accurate screening test for large populations.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.42.8.3707-3710.2004

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