Reemerging Threat of Epidemic Typhus in Algeria

Author:

Mokrani K.1,Fournier P. E.2,Dalichaouche M.3,Tebbal S.1,Aouati A.3,Raoult D.2

Affiliation:

1. Clinique des Maladies Infectieuses, Centre Hospitalier de Batna, Batna

2. Unité des Rickettsies, IFR 48, CNRS UMR 6020, Faculté de Médecine, Université de la Méditerranée, 13385 Marseilles Cédex 5, France

3. Service des Maladies Infectieuses, Centre Hospitalier de Constantine, Constantine, Algeria

Abstract

ABSTRACT We report a case of epidemic typhus in a patient from the Batna region of Algeria, who presented with generalized febrile exanthema. The clinical diagnosis was confirmed by serological cross-adsorption followed by Western blotting. Our report emphasizes the threat of epidemic typhus in the highlands of Algeria.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference22 articles.

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2. Ching, W. M., G. A. Dasch, M. Carl, and M. E. Dobson. 1990. Structural analyses of the 120-kDa serotype protein antigens of typhus group rickettsiae. Comparison with other S-layer proteins. Ann. N. Y. Acad. Sci.590:334-351.

3. Dasch, G. A., and A. L. Bourgeois. 1981. Antigens of the typhus group of rickettsiae: importance of the species-specific surface antigens in eliciting immunity, p. 61-69. In W. Burgdorfer and R. L. Anacker (ed.), Rickettsiae and rickettsial diseases. Academic Press, Inc., New York, N.Y.

4. Serological response of patients suffering from primary and recrudescent typhus: comparison of complement fixation reaction, Weil-Felix test, microimmunofluorescence, and immunoblotting

5. Goldwasser, R. A., and C. C. Shepard. 1959. Fluorescent antibody methods in the differentiation of murine and epidemic typhus fever: specific changes resulting from previous immunization. J. Immunol.82:373-380.

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