Pharmacokinetic Interpretation of Cephradine Levels in Serum After Intravenous and Extravascular Administration in Humans-Reference-Cited by-同舟云学术

Pharmacokinetic Interpretation of Cephradine Levels in Serum After Intravenous and Extravascular Administration in Humans

Published:1976-08 Issue:2 Volume:10 Page:283-287
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Rattie Elisabeth S.¹,Bernardo Peter D.¹,Ravin Louis J.¹

Affiliation:

1. Research and Development Division, Smith Kline and French Laboratories, Philadelphia, Pennsylvania 19101

Abstract

Pharmacokinetic parameters were calculated from intravenous data based upon a two-compartment open model. These parameters were subsequently used to determine the absorption rates and bioavailability of cephradine administered intramuscularly and orally. The results indicate that cephradine obeys dose-independent kinetics and that biological availability is complete from all dosage forms.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.10.2.283

Reference10 articles.

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5. Cephradine in the treatment of intestinal infections caused by Shigella or Salmonella organisms;Landa L.;Curr. Ther. Res. Clin. Exp.,1972

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