Genotypic Stability of Methicillin Resistance in Staphylococcus aureus at Supraoptimal Temperature

Author:

Rozgonyi Ferenc1

Affiliation:

1. Institute of Microbiology, University Medical School of Debrecen, H-4012 Debrecen, Hungary

Abstract

Methicillin resistance in a highly resistant mutant of Staphylococcus aureus could not be diminished by elevated temperature. After 100 subcultures at 43°C the resistance to methicillin was retained when determined at 37°C.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference16 articles.

1. Loss of methicillin-resistance from resistant strains of Staphylococcus aureus;Al Salihy S. M.;Lancet,1972

2. The effect of temperature on resistance of Staphylococcus aureus to methicillin and some other antibiotics;Annear D. I.;Med. J. Aust.,1968

3. Barrett F. F. R. F. McGehee Jr. and M. Finland. 1968. Methicillin-resistant Staphylococcus aureus at VOL. 10 1976

4. La resistance naturelle des Staphylococues a la methicilline et l'oxacilline;Chabbert Y. A.;Rev. Fr. Etud. Clin. Biol.,1965

5. Penicillinase production and intrinsic resistance to penicillins in methicillin-resistant cultures ofStaphylococcus aureus;Dyke K. G. H.;J. Med. Microbiol.,1969

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