Heteroresistance to Vancomycin in Enterococcus faecium-Reference-Cited by-同舟云学术

Heteroresistance to Vancomycin in Enterococcus faecium

Published:2001-09 Issue:9 Volume:39 Page:3379-3381
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Alam M. Rabiul¹²,Donabedian Susan²,Brown William³⁴,Gordon James¹⁴,Chow Joseph W.¹⁵⁴,Zervos Marcus J.¹²⁴,Hershberger Ellie²

Affiliation:

1. Division of Infectious Disease, Department of Medicine,1 and

2. William Beaumont Hospital,2 Royal Oak, and

3. DMC University Laboratories,3

4. Department of Medicine, Wayne State University,4 Detroit, Michigan

5. Veterans Administration Medical Center,5 and

Abstract

ABSTRACT This study presents the first report of vancomycin heteroresistance in an Enterococcus faecium isolate from a patient. The original isolate was susceptible in vitro to vancomycin. E-tests showed growth of subcolonies in a zone of inhibition with a vancomycin MIC of >256 μg/ml. Both the susceptible and resistant colonies were from the same strain as determined by PFGE, and both contained the vanA gene as determined by PCR.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.39.9.3379-3381.2001

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