Human Papillomavirus 16 E2 Interaction with TopBP1 Is Required for E2 and Viral Genome Stability during the Viral Life Cycle-Reference-Cited by-同舟云学术

Human Papillomavirus 16 E2 Interaction with TopBP1 Is Required for E2 and Viral Genome Stability during the Viral Life Cycle

Published:2023-03-30 Issue:3 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Prabhakar Apurva T.¹,James Claire D.¹,Fontan Christian T.¹,Otoa Raymonde¹,Wang Xu¹,Bristol Molly L.¹²,Hill Ronald D.¹,Dubey Aanchal¹,Morgan Iain M.¹²^ORCID

Affiliation:

1. Virginia Commonwealth University (VCU), Philips Institute for Oral Health Research, School of Dentistry, Richmond, Virginia, USA

2. VCU Massey Cancer Center, Richmond, Virginia, USA

Abstract

Human papillomaviruses are pathogens that cause a host of diseases ranging from benign warts to cancers. There are no therapeutics available for combating these diseases that directly target viral proteins or processes; therefore, we must enhance our understanding of HPV life cycles to assist with identifying novel treatments.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00063-23

Reference59 articles.

1. Papillomaviruses in the causation of human cancers — a brief historical account

2. Carcinogenic human papillomavirus infection