Molecular Epidemiology of VIM-4 Metallo-β-Lactamase-Producing Pseudomonas sp. Isolates in Hungary

Author:

Libisch Balázs1,Muzslay Mónika2,Gacs Mária1,Minárovits János3,Knausz Márta4,Watine Joseph5,Ternák Gábor6,Kenéz Éva7,Kustos Ildikó8,Rókusz László9,Széles Klára10,Balogh Boglárka1,Füzi Miklós1

Affiliation:

1. Department of Bacteriology, National Center for Epidemiology, 1097 Budapest, Hungary

2. Department of Molecular Epidemiology, National Center for Epidemiology, 1097 Budapest, Hungary

3. Microbiological Research Group, National Center for Epidemiology, 1529 Budapest, Hungary

4. Aladár Petz County Teaching Hospital, 9023 Győr, Hungary

5. Laboratoire de Biologie Polyvalente, Hôpital Général, 12027 Rodez Cédex 9, France

6. Department of Infectious Diseases, Baranya County Hospital, 7623 Pécs, Hungary

7. Laboratory of Microbiology, Baranya County Hospital, 7623 Pécs, Hungary

8. Department of Medical Microbiology and Immunology, University of Pécs, 7643 Pécs, Hungary

9. Department of Internal Medicine, Central Military Hospital, 1553 Budapest, Hungary

10. Department of Epidemiology, National Public Health Service, 9024 Győr, Hungary

Abstract

ABSTRACT VIM metallo-β-lactamase-producing serotype O11 or O12 Pseudomonas aeruginosa isolates infecting or colonizing 19 patients from seven hospitals in Hungary were characterized between October 2003 and November 2005. Macrorestriction analysis revealed the involvement of hospitals from three different towns in northwest Hungary in an outbreak caused by VIM-4-producing P. aeruginosa .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference23 articles.

1. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing. Fifteenth informational supplement. M100-S15. Clinical and Laboratory Standards Institute Wayne Pa.

2. Outbreak of Carbapenem-Resistant Pseudomonas aeruginosa Producing VIM-8, a Novel Metallo-β-Lactamase, in a Tertiary Care Center in Cali, Colombia

3. Molecular Epidemiology of Acquired-Metallo-β-Lactamase-Producing Bacteria in Poland

4. Grattard, F., O. G. Gaudin, B. Pozzeto, A. Ris, and A. D. Mbida. 1993. Genotypic homogeneity of nosocomial Pseudomonas aeruginosa O12 strains demonstrated by analysis of protein profiles, DNA fingerprints and rRNA gene restriction patterns. Eur. J. Clin. Microbiol. Infect. Dis.12:57-61.

5. Johan Béla National Public Health Institute. 1997. Antibiotic susceptibility of the most important gram-negative bacteria, p. 159-173. In The 1996 annual report of the Johan Béla National Public Health Institute. Johan Béla National Public Health Institute, Budapest, Hungary. (In Hungarian.)

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