Characterization of GP110, a neutrophil surface protein

Author:

Tripathi S C1,Van Dyke T E1

Affiliation:

1. Emory University School of Postgraduate Dentistry, Atlanta, Georgia 30322.

Abstract

Localized juvenile periodontosis is associated with a defect of neutrophil chemotaxis that is characterized by selective depletion of a surface protein with a molecular mass of 110 kDa (GP110). Data on partial characterization of GP110 suggest that it is a glycoprotein which is enriched in Lys, Glu, His, Leu, and Ala residues.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference20 articles.

1. The case for periodontosis as a clinical entity;Baer P. N.;J. Periodontol.,1971

2. Defective polymorphonuclear leukocyte function in a human periodontal disease;Cianciola L. J.;Nature (London),1977

3. Defective neutrophil chemotaxis in juvenile periodontitis;Clark R. A.;Infect. Immun.,1977

4. cDNA cloning and complete primary structure of the a-subunit of a leukocyte adhesion glycoprotein, p150,95;Corbi A. L.;EMBO J.,1987

5. A cell surface differentiation antigen involved in human neutrophil chemotaxis and degranulation;Cotter T. G.;Clin. Exp. Immunol.,1983

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