Detection of Yersinia enterocolitica heat-stable enterotoxin by suckling mouse bioassay

Author:

Nunes M P,Ricciardi I D

Abstract

A comparison of heat-stable enterotoxins from Escherichia coli and Yersinia enterocolitica by the suckling mouse bioassay showed that whereas E. coli heat-stable enterotoxin evoked a maximum ratio of gut weight to remaining body weight after a 4-h incubation period, the maximum ratio for Y. enterocolitica was achieved at 2 h, decreasing thereafter to values regarded as negative (less than 0.083). This action of Y. enterocolitica heat-stable enterotoxin may give false-negative results for the standard suckling mouse bioassay.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference13 articles.

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3. Carter P. B. C. F. Varga and E. E. Keet. 197:3. New strain of Yersinia enterocolitica pathogenic for rodents. Apple. Microbiol. 26:11)106-1018.

4. Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu;Dean A. G.;J. Invest. Dis.,1972

5. Plasmid associated with pathogenicity and calcium dependency of Yersinia enterocolitica;Gemski P.;Infect. Immun.,1980

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