Ancestry of a human endogenous retrovirus family

Author:

Mariani-Costantini R1,Horn T M1,Callahan R1

Affiliation:

1. Section on Oncogenetics, National Cancer Institute, Bethesda, Maryland 20892.

Abstract

The human endogenous retrovirus type II (HERVII) family of HERV genomes has been found by Southern blot analysis to be characteristic of humans, apes, and Old World monkeys. New World monkeys and prosimians lack HERVII proviral genomes. Cellular DNAs of humans, common chimpanzees, gorillas, and orangutans, but not lesser ape lar gibbons, appear to contain the HERVII-related HLM-2 proviral genome integrated at the same site (HLM-2 maps to human chromosome 1). This suggests that the ancestral HERVII retrovirus(es) entered the genomes of Old World anthropoids by infection after the divergence of New World monkeys (platyrrhines) but before the evolutionary radiation of large hominoids.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference25 articles.

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2. Andrews P. 1985. Family groups systematics and evolution among catarrhine primates p. 14-22. In E. Delson (ed.) Ancestors: the hard evidence. Alan R. Liss Inc. New York.

3. Cloned endogenous retroviral sequences from human DNA;Bonner T. I.;Proc. Natl. Acad. Sci. USA,1982

4. Callahan R. 1988. Two families of human endogenous retroviral genomes p. 91-100. In Banbury report 30: eukaryotic transposable elements as mutagenic agents. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y.

5. A new class of endogenous human retroviral genomes;Callahan R.;Science,1985

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