Unusual nucleotide arrangement with repeated sequences in the Escherichia coli K-12 chromosome

Author:

Nakata A1,Amemura M1,Makino K1

Affiliation:

1. Department of Experimental Chemotherapy, Osaka University, Japan.

Abstract

Between 59 and 60 min on the Escherichia coli genetic map, there is a highly conserved sequence of 29 base pairs, containing an inverted repeat of seven base pairs that appears 14 times, 32 or 33 base pairs apart, downstream of the iap gene coding region. About 24 kilobase pairs downstream of the 14 repeats, a similar 29-base-pair sequence with a spacing of 32 base pairs appears seven times. Nucleotide sequences hybridizing with the 29-base-pair fragment were also detected in Shigella dysenteriae and Salmonella typhimurium but not in Klebsiella pneumoniae or Pseudomonas aeruginosa.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference13 articles.

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3. Pedigrees of some mutant strains of Escherichia coli K-12;Bachmann B. J.;Bacteriol. Rev.,1972

4. Palindromic units: a case of highly repetitive DNA sequences in bacteria;Gilson E.;Trends Genet.,1987

5. Modification of T-even phages due to defective glucosylation of their DNA;Hattman S.;Proc. Natl. Acad. Sci. USA,1963

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