Replication of Wild-Type and Mutant Human Cytomegalovirus in Life-Extended Human Diploid Fibroblasts-Reference-Cited by-同舟云学术

Replication of Wild-Type and Mutant Human Cytomegalovirus in Life-Extended Human Diploid Fibroblasts

Published:2000-11-15 Issue:22 Volume:74 Page:10816-10818
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Bresnahan Wade A.¹,Hultman Gretchen E.¹,Shenk Thomas¹

Affiliation:

1. Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014

Abstract

ABSTRACT A cDNA encoding the catalytic subunit of human telomerase was used to generate life-extended derivatives of primary human diploid fibroblasts. The life-extended cells supported efficient human cytomegalovirus (HCMV) replication. A subclone of the life-extended cells was generated containing the HCMV UL82 gene and used to isolate and propagate a virus that exhibited a profound growth defect after infection at a low input multiplicity.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.74.22.10816-10818.2000

Reference14 articles.

1. Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle

2. Extension of life-span by introduction of telomerase into normal human cells;Bodnar A. G.;Science,1998

3. Comparison of MRC-5 and U-373MG astrocytoma cells for detection of cytomegalovirus in shell vial centrifugation cultures;Boeckh M.;Eur. J. Clin. Microbiol. Infect. Dis.,1991

4. Replication of human cytomegalovirus in endothelial cells;Ho D. D.;J. Infect. Dis.,1984

5. Human cytomegalovirus productively infects primary differentiated macrophages

Cited by 105 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes;PLOS Pathogens;2023-12-01

2. ASK1 inhibitors are potential pan-antiviral drugs, which dampen replication of diverse viruses including SARS-CoV2;Antiviral Research;2023-12

3. Herpes Simplex Virus-1 ICP27 Nuclear Export Signal Mutants Exhibit Cell Type-Dependent Deficits in Replication and ICP4 Expression;Journal of Virology;2023-07-27

4. CMPK2 restricts Zika virus replication by inhibiting viral translation;PLOS Pathogens;2023-04-19

5. Differential Cellular Sensing of Fusion from within and Fusion from without during Virus Infection;Viruses;2023-01-21