Molecular Characterization of Ofloxacin-Resistant Mycobacterium tuberculosis Strains from Russia-Reference-Cited by-同舟云学术

Molecular Characterization of Ofloxacin-Resistant Mycobacterium tuberculosis Strains from Russia

Published:2008-08 Issue:8 Volume:52 Page:2937-2939
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Mokrousov Igor¹²,Otten Tatiana³,Manicheva Olga³,Potapova Yulia³,Vishnevsky Boris³,Narvskaya Olga¹,Rastogi Nalin²

Affiliation:

1. Laboratory of Molecular Microbiology, St. Petersburg Pasteur Institute, 197101 St. Petersburg, Russia

2. Unité de la Tuberculose et des Mycobactéries, Institut Pasteur de Guadeloupe, Abymes 97183, Guadeloupe, France

3. Laboratory of Microbiology of Tuberculosis, The Research Institute of Phthisiopulmonology, 193036 St. Petersburg, Russia

Abstract

ABSTRACT In this work, we studied the variation in the gyrA and gyrB genes in ofloxacin- and multidrug-resistant Mycobacterium tuberculosis strains circulating in northwest Russia. Comparison with spoligotyping data suggested that similar to the spread of multidrug-resistant tuberculosis, the spread of fluoroquinolone-resistant tuberculosis in Russia may be due, at least partly, to the prevalence of the Beijing genotype in a local population of M. tuberculosis .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00036-08

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