Affiliation:
1. Department of Microbiology, University of Minnesota, St. Paul 55108.
Abstract
Two genes (mcrA and mcrB) from Streptomyces lavendulae that together confer resistance to mitomycin C were identified. This DNA appears to comprise a polycistronic operon with a drug-inducible leaderless mRNA. The deduced amino acid sequence of mcrA shows similarity to sequences of a special class of bacterial, plant, and animal oxygen oxidoreductases.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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