Th17 Cells Provide Mucosal Protection against Gastric Trypanosoma cruzi Infection-Reference-Cited by-同舟云学术

Th17 Cells Provide Mucosal Protection against Gastric Trypanosoma cruzi Infection

Published:2021-06-16 Issue:7 Volume:89 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Cai Catherine W.¹²,Eickhoff Christopher S.¹,Meza Krystal A.¹,Blase Jennifer R.¹²,Audette Rebecca E.¹,Chan David H.¹,Bockerstett Kevin A.²,DiPaolo Richard J.²,Hoft Daniel F.¹²^ORCID

Affiliation:

1. Division of Infectious Diseases, Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA

2. Department of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, Saint Louis, Missouri, USA

Abstract

Trypanosoma cruzi is the intracellular parasite of Chagas disease, a chronic condition characterized by cardiac and gastrointestinal morbidity. Protective immunity requires CD4 + T cells, and Th1 cells and gamma interferon (IFN-γ) are important players in host defense.

Funder

HHS | National Institutes of Health

American Heart Association

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00738-20

Reference30 articles.

1. Chagas disease

2. An Estimate of the Burden of Chagas Disease in the United States