Spontaneous switching of the sucrose-promoted colony phenotype in Streptococcus sanguis

Author:

Tardif G1,Sulavik M C1,Jones G W1,Clewell D B1

Affiliation:

1. Department of Microbiology and Immunology, School of Medicine, University of Michigan, Ann Arbor 48109-0402.

Abstract

Streptococcus sanguis on media containing 3% sucrose gives rise to characteristic hard cohesive colonies (designated Spp+). Populations of Spp+ bacteria (strain Challis) on sucrose media switch to a soft noncohesive phenotype (designated Spp-) at a frequency of 10(-4) to 10(-3). Spp- bacteria switch back to Spp+ bacteria at a similar frequency. Successive rounds of Spp variation were observed. The Spp phenotypic switch was associated with changes in extracellular glucosyltransferase activity.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference32 articles.

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