TLA-2, a Novel Ambler Class A Expanded-Spectrum β-Lactamase-Reference-Cited by-同舟云学术

TLA-2, a Novel Ambler Class A Expanded-Spectrum β-Lactamase

Published:2005-11 Issue:11 Volume:49 Page:4767-4770
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Girlich Delphine¹,Poirel Laurent¹,Schlüter Andreas²,Nordmann Patrice¹

Affiliation:

1. Service de Bactériologie-Virologie, Université Paris XI, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France

2. Fakultät für Biologie, Lehrstuhl für Genetik, Universität Bielefeld, D-33615 Bielefeld, Germany

Abstract

ABSTRACT β-Lactamase TLA-2 is encoded by a 47-kb plasmid isolated from an unidentified bacterial strain from a wastewater treatment plant. TLA-2 is an Ambler class A β-lactamase that shares 52% amino acid identity with CGA-1 from Chryseobacterium gleum and 51% with TLA-1 from Escherichia coli . The enzyme hydrolyzes mostly cephalosporins.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.11.4767-4770.2005

Reference25 articles.

1. Ambler, R. P., A. F. W. Coulson, J.-M. Frère, J. M. Ghuysen, B. Joris, M. Forsman, R. C. Lévesque, G. Tiraby, and S. G. Wakey. 1991. A standard numbering scheme for class A β-lactamases. Biochem. J.276:269-272.

2. Functional and Structural Characterization of the Genetic Environment of an Extended-Spectrum β-Lactamase bla VEB Gene from a Pseudomonas aeruginosa Isolate Obtained in India

3. Bauernfeind, A., I. Stemplinger, R. Jungwirth, S. Ernst, and J. M. Casellas. 1996. Sequences of β-lactamase genes encoding CTX-M-1 (MEN-1) and CTX-M-2 and relationship of their amino acid sequences with those of other β-lactamases. Antimicrob. Agents Chemother.40:509-513.

4. Molecular and Biochemical Characterization of Ambler Class A Extended-Spectrum β-Lactamase CGA-1 from Chryseobacterium gleum

5. Genetic-Biochemical Analysis and Distribution of the Ambler Class A β-Lactamase CME-2, Responsible for Extended-Spectrum Cephalosporin Resistance in Chryseobacterium ( Flavobacterium ) meningosepticum

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