Antipneumococcal Activity of Dalbavancin Compared to Other Agents

Author:

Lin Gengrong1,Smith Kathy1,Ednie Lois M.1,Appelbaum Peter C.1

Affiliation:

1. Department of Pathology, Hershey Medical Center, Hershey, Pennsylvania 17033

Abstract

ABSTRACT Against 307 pneumococci of various resistotypes, dalbavancin MICs were 0.008 to 0.125 μg/ml. All strains were susceptible to vancomycin, teicoplanin, linezolid, and quinupristin-dalfopristin. Dalbavancin at 2× MIC was bactericidal against all 10 pneumococci tested after 24 h. Vancomycin and teicoplanin killed 10 and 8 strains, respectively, at 2× MIC after 24 h.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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