Genomic Epidemiology and Strain Taxonomy of Corynebacterium diphtheriae

Author:

Guglielmini Julien1,Hennart Melanie23,Badell Edgar24,Toubiana Julie245,Criscuolo Alexis1,Brisse Sylvain24ORCID

Affiliation:

1. Institut Pasteur, Université de Paris, Bioinformatics and Biostatistics Hub, Department of Computational Biology, Paris, France

2. Institut Pasteur, Université de Paris, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France

3. Sorbonne Université, Collège Doctoral, Paris, France

4. National Reference Center for the Corynebacteria of the Diphtheriae Complex, Paris, France

5. Université de Paris, Service de Pédiatrie Générale et Maladies Infectieuses, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France

Abstract

Corynebacterium diphtheriae is highly transmissible and can cause large diphtheria outbreaks where vaccination coverage is insufficient. Sporadic cases or small clusters are observed in high-vaccination settings.

Funder

H2020 one health EJP

Investissement d'avenir

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference60 articles.

1. Diphtheria and its Etiological Agents

2. The first case of septicemia due to nontoxigenic Corynebacterium diphtheriae in Poland: case report

3. Diphtheria

4. ECDC. 2021. Diphtheria: annual epidemiological report for 2018. European Centre for Disease Prevention and Control Solna Sweden. https://www.ecdc.europa.eu/sites/default/files/documents/diphtheria-annual-epidemiological-report-2018.pdf.

5. Outbreak investigation for toxigenic Corynebacterium diphtheriae wound infections in refugees from Northeast Africa and Syria in Switzerland and Germany by whole genome sequencing

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