GES-11, a Novel Integron-Associated GES Variant in Acinetobacter baumannii-Reference-Cited by-同舟云学术

GES-11, a Novel Integron-Associated GES Variant in Acinetobacter baumannii

Published:2009-08 Issue:8 Volume:53 Page:3579-3581
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Moubareck Carole¹,Brémont Sylvie¹,Conroy Marie-Christine²,Courvalin Patrice¹,Lambert Thierry¹

Affiliation:

1. Institut Pasteur, Unité des Agents Antibactériens, Centre National de Référence de la Résistance aux Antibiotiques, 75724 Paris Cedex 15

2. Laboratoire de Bactériologie, CHU, 54035 Nancy Cedex, France

Abstract

ABSTRACT New extended-spectrum β-lactamase GES-11 was detected in Acinetobacter baumannii BM4674. The enzyme conferred resistance to β-lactams, including aztreonam, and reduced susceptibility to carbapenems. The structural gene was part of a class 1 integron borne by self-transferable plasmid pIP847. GES-type β-lactamases have not been reported previously in A. baumannii .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00072-09

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