High In Vitro Susceptibility to the First-in-Class Spiropyrimidinetrione Zoliflodacin among Consecutive Clinical Neisseria gonorrhoeae Isolates from Thailand and South Africa-Reference-Cited by-同舟云学术

High In Vitro Susceptibility to the First-in-Class Spiropyrimidinetrione Zoliflodacin among Consecutive Clinical Neisseria gonorrhoeae Isolates from Thailand and South Africa

Published:2019-12 Issue:12 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Jacobsson Susanne¹,Kularatne Ranmini²,Kittiyaowamarn Rossaphorn³,Maseko Venessa²,Paopang Porntip³,Sangprasert Pongsathorn³,Sirivongrangson Pachara⁴,Piddock Laura⁵,Wi Teodora⁶,Alirol Emilie⁵,Unemo Magnus¹

Affiliation:

1. WHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

2. Centre for HIV and STIs, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa

3. Bangrak STI Center, Bureau of AIDS, TB, and STIs, Department of Disease Control, Ministry of Public Health, Bangkok, Thailand

4. Department of Disease Control, Ministry of Public Health, Bangkok, Thailand

5. Global Antibiotic Research & Development Partnership, Geneva, Switzerland

6. Department of Reproductive Health, World Health Organization, Geneva, Switzerland

Abstract

We evaluated the in vitro susceptibility to the first-in-class spiropyrimidinetrione zoliflodacin among recent consecutive clinical Neisseria gonorrhoeae isolates cultured in Thailand ( n = 99) (in 2018) and South Africa ( n = 100) (in 2015 to 2017).

Funder

Global Antibiotic Research & Development Partnership

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01479-19

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