Activity of Tetracycline, Doxycycline, and Minocycline Against Methicillin-Susceptible and -Resistant Staphylococci-Reference-Cited by-同舟云学术

Activity of Tetracycline, Doxycycline, and Minocycline Against Methicillin-Susceptible and -Resistant Staphylococci

Published:1974-10 Issue:4 Volume:6 Page:411-414
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Minuth J. N.¹²,Holmes T. M.¹²,Musher D. M.¹²

Affiliation:

1. Department of Medicine, Veterans Administration Hospital, Houston, Texas 77031

2. Baylor College of Medicine, Houston, Texas 77025

Abstract

Tetracycline, doxycycline, and minocycline were evaluated for their antibacterial activity against methicillin-susceptible and -resistant isolates of Staphylococcus . At clinically achievable levels both doxycycline and minocycline were more active than tetracycline against methicillin-susceptible organisms. Tetracycline and doxycycline had no activity against methicillin-resistant staphylococci, whereas minocycline at 2 μg/ml inhibited six of 13 strains and, at 3 μg/ml, 10 of 13 strains.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.6.4.411

Reference15 articles.

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3. Growing clinical significance of methicillin-resistant Staphylococcus aureus;Benner J. E.;Lancet,1968

4. Clinical pharmacological studies with minocycline;Bernard B.;J. Clin. Pharmacol.,1971

5. Comparison of treatments with several antibiotics in experimental infection due to methicillin-resistant Staphylococcus aureus;Bulger R. J.;J. Infect. Dis.,1972

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