Photodynamic Inactivation with Proflavine: Quantitative Comparison with Iodo-Deoxyuridine-Reference-Cited by-同舟云学术

Photodynamic Inactivation with Proflavine: Quantitative Comparison with Iodo-Deoxyuridine

Published:1973-04 Issue:4 Volume:7 Page:518-519
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Varnell Emily D.¹,Kaufman Herbert E.¹

Affiliation:

1. Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida 32601

Abstract

Photodynamic inactivation utilizing proflavine and light was quantitatively compared with the therapeutic antiviral effect of iodo-deoxyuridine in experimental herpetic keratitis in the rabbit. This rabbit model, which has been shown to be highly predictive for antiviral therapy in man, indicates that the photodynamic effect, though definite, is minimal.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.7.4.518-519.1973

Reference11 articles.

1. In vivo studies with antiviral agents;Kaufman H. E.;Ann. N. Y. Acad. Sci.,1965

2. Corneal toxicity of cytosine arabinoside;Kaufman H. E.;Arch. Ophthalmol.,1964

3. Chemotherapy of herpes iritis with adenine arabinoside and cytarabinle;Kaufman H. E.;Arch. Ophthalmol.,1970

4. Therapeutic antiviral action of 5-trifluoromethy1-2'- deoxyuridine;Kaufman H. E.;Science,1964

5. IDU therapy of herpes simplex;Kaufman H. E.;Arch. Ophthalmol.,1962

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