Open Development and Clinical Validation of Multiple 3D-Printed Nasopharyngeal Collection Swabs: Rapid Resolution of a Critical COVID-19 Testing Bottleneck-Reference-Cited by-同舟云学术

Open Development and Clinical Validation of Multiple 3D-Printed Nasopharyngeal Collection Swabs: Rapid Resolution of a Critical COVID-19 Testing Bottleneck

Published:2020-07-23 Issue:8 Volume:58 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Callahan Cody J.¹,Lee Rose²³,Zulauf Katelyn E.²⁴,Tamburello Lauren⁵,Smith Kenneth P.²⁴,Previtera Joe⁶,Cheng Annie²,Green Alex²⁴,Abdul Azim Ahmed³⁷,Yano Amanda⁸,Doraiswami Nancy⁹,Kirby James E.²⁴,Arnaout Ramy A.²⁴¹⁰

Affiliation:

1. Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

2. Clinical Microbiology Laboratories, Division of Clinical Pathology, Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

3. Division of Infectious Disease, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

4. Harvard Medical School, Boston, Massachusetts, USA

5. Division of Urologic Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

6. Division of Respiratory Therapy, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

7. Division of Infection Control/Hospital Epidemiology, Silverman Institute for Healthcare Quality and Safety, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

8. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

9. Division of Perioperative Services, Department of Central Processing, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

10. Division of Clinical Informatics, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

Abstract

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a severe international shortage of the nasopharyngeal swabs that are required for collection of optimal specimens, creating a critical bottleneck blocking clinical laboratories’ ability to perform high-sensitivity virological testing for SARS-CoV-2. To address this crisis, we designed and executed an innovative, cooperative, rapid-response translational-research program that brought together health care workers, manufacturers, and scientists to emergently develop and clinically validate new swabs for immediate mass production by 3D printing.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Center for Advancing Translational Sciences

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00876-20

Reference22 articles.

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