GenSeizer: a Multiplex PCR-Based Targeted Gene Sequencing Platform for Rapid and Accurate Identification of Major Mycobacterium Species

Author:

Li Bing1,Xu Liyun1,Guo Qi12,Chen Jianhui12,Zhang Yanan3,Huang Wenpan3,Zhang Zhemin1,Han Lizhong4,Xu Xiaogang5,Chu Haiqing16ORCID

Affiliation:

1. Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China

2. Tongji University School of Medicine, Shanghai, China

3. Shanghai Morgene Biotechnology Co., Ltd., Shanghai, China

4. Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

5. Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China

6. Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China

Abstract

Mycobacterium tuberculosis and nontuberculous mycobacterium (NTM) infections often exhibit similar clinical symptoms. Timely and effective treatment relies on the rapid and accurate identification of species and resistance genotypes.

Funder

Medical Guide Program of Shanghai Science and Technology Committee

New Frontier Technology Joint Project of Municipal Hospital, Shanghai Shenkang Hospital Development Center

Shanghai Municipal Health Committee Excellent Talents Training Program

General Project of Shanghai Municipal Health Committee

Project of Top Clinical Medicine Centers and Key Disciplines Construction in Shanghai

Natural Science Foundation of Shanghai

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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