Structure and Genome Organization of AFV2, a Novel Archaeal Lipothrixvirus with Unusual Terminal and Core Structures

Author:

Häring Monika12,Vestergaard Gisle3,Brügger Kim3,Rachel Reinhard2,Garrett Roger A.3,Prangishvili David12

Affiliation:

1. Unité de Biologie Moléculaire du Gène chez les Extrêmophiles, Institut Pasteur, rue Dr. Roux 25, 75724 Paris Cedex 15, France

2. Department of Microbiology, Archaea Centre, University of Regensburg, Universitätsstrasse 31, D-93053 Regensburg, Germany

3. Danish Archaea Centre, Institute of Molecular Biology, Copenhagen University, Sølvgade 83H, DK-1307 Copenhagen, Denmark

Abstract

ABSTRACT A novel filamentous virus, AFV2, from the hyperthermophilic archaeal genus Acidianus shows structural similarity to lipothrixviruses but differs from them in its unusual terminal and core structures. The double-stranded DNA genome contains 31,787 bp and carries eight open reading frames homologous to those of other lipothrixviruses, a single tRNA Lys gene containing a 12-bp archaeal intron, and a 1,008-bp repeat-rich region near the center of the genome.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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