Importance of Antirabies Revaccination for an Adequate Antirabies Protection in Bovine Newborns

Author:

Filho O. A.12,Megid J.12,Geronutti L.12,Ratti J.12,Kataoka A. P. A. G.12,Martorelli L. F. A.12

Affiliation:

1. UNESP—School of Veterinary Medicine and Animal Science, Department of Veterinary Hygiene and Public Health, Botucatu-SP, Brazil

2. Zoonosis Control Center—Rabies Laboratory, São Paulo-SP, Brazil

Abstract

ABSTRACT The transfer of antirabies immunoglobulins in cows that were prime vaccinated and cows that were revaccinated against rabies correlated to the serum titers in their offspring was evaluated. The results demonstrated that revaccination against rabies during pregnancy induces neutralizing antibody titers at a protective level that are transferred directly to calves through colostrum and reinforce the importance of revaccination for improved colostral antibody transfer and offspring protection against rabies.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Reference24 articles.

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2. Albas, A., O. L. Fontolan, P. E. Pardo, H. Bremer Neto, and A. Sartori. 2006. Interval between first dose and booster affected antibody production in cattle vaccinated against rabies. J. Venom. Anim. Toxins Incl. Trop. Dis.12:476-486.

3. Atanasiu, P. 1973. Quantitative assay and potency test of antirabies serum and immunoglobulin. Monogr. Ser. World Health Organ.23:314-318.

4. Bunn, T. O. 1988. Vaccines and vaccination of domestic animals, vol. 2, p. 321-333. In J. B. Campbell and K. M. Charlton (ed.), Rabies. Kluwer, Boston, MA.

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