Isolation, Identification, and Synthesis of 2,3-Diamino-2,3-Dideoxyglucuronic Acid: a Component of Propionibacterium acnes Cell Wall Polysaccharide

Author:

Cummins C. S.1,White R. H.2

Affiliation:

1. Department of Anaerobic Microbiology Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061

2. Department of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061

Abstract

A previously undescribed component of the cell wall polysaccharide of Propionibacterium acnes , 2,3-diamino-2,3-dideoxyglucuronic acid, has been identified and synthesized. The component occurs to the extent of about 3 to 5% in the wall polysaccharides of P. acnes types I and II and in Propionibacterium avidum types I and II; it also appears to be present, but in much smaller amounts, in the cell wall of Propionibacterium granulosum .

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference33 articles.

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2. Chemical and biological properties of a purified lympho-rticular stimulating fraction of Corynebacterium parvum. (Propionibacterium acnes, type 1);Adlan C.;J. Med. Microbiol.,1979

3. The synthesis of uronic acids;Barker S. A.;Chem. Ind.,1951

4. The effect of acidic polysaccharides and prostaglandin-like substances isolated from Propionibacterium acnes on granulocyte chemotaxis;Debbdn J.;Experientia,1979

5. An aminohexuronic acid as the principal hydrolytic component of the VI antigen;Clerk W. R.;J. Biol. Chem.,1958

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