High-Resolution Typing of Staphylococcus epidermidis Based on Core Genome Multilocus Sequence Typing To Investigate the Hospital Spread of Multidrug-Resistant Clones

Author:

Jamet Anne12,Guglielmini Julien3,Brancotte Bryan3,Coureuil Mathieu1ORCID,Euphrasie Daniel1,Meyer Julie1,Roux Johanna1,Barnier Jean-Philippe12,Bille Emmanuelle12,Ferroni Agnès2,Magny Jean-François4,Bôle-Feysot Christine56,Charbit Alain1,Nassif Xavier12,Brisse Sylvain7ORCID

Affiliation:

1. Université de Paris, INSERM U1151 - CNRS UMR 8253, Institut Necker-Enfants Malades, Team: Pathogenesis of Systemic Infections, Paris, France

2. Department of Clinical Microbiology, Necker Enfants-Malades Hospital, AP-HP. Centre Université de Paris, Paris, France

3. Institut Pasteur, Bioinformatics and Biostatistics Hub, Département Biologie Computationnelle, Paris, France

4. Neonatal Intensive Care Unit, Necker Enfants-Malades Hospital, AP-HP. Centre Université de Paris, Paris, France

5. INSERM UMR 1163, Genomics platform, Université de Paris, Imagine Institute, Paris, France

6. Genomic Core Facility, Imagine Institute-Structure Fédérative de Recherche Necker, INSERM U1163, Paris, France

7. Institut Pasteur, Biodiversity and Epidemiology of Bacterial Pathogens Unit, Paris, France

Abstract

Staphylococcus epidermidis is a pathogen emerging worldwide as a leading cause of health care-associated infections. A standardized high-resolution typing method to document transmission and dissemination of multidrug-resistant S. epidermidis strains is needed.

Funder

Assistance Publique - Hôpitaux de Paris

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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