Author:
Cannon J G,Black W J,Nachamkin I,Stewart P W
Abstract
A hybridoma derived from a mouse immunized with gonococcal outer membranes produced an antibody, designated H.8, that bound to all strains of Neisseria gonorrhoeae and N. meningitidis tested, and to N. lactamica and N. cinerea, but only rarely to other nonpathogenic Neisseria species. Studies with the gonococcal strain used in production of the antibody showed that the antibody bound to a surface-exposed, protease-sensitive, and heat-modifiable outer membrane antigen that we believe is distinct from previously described gonococcal outer membrane proteins.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference34 articles.
1. Brinton C. C. J. Bryan J. Dillon N. Guerina L. J. Jacobson A. Labic S. Lee A. Levine S. Lim J. McMichael S. Polen K. Rogers A. To and S. To. 1978. Uses of pili in gonorrhea control: role of bacterial pili in disease purification and properties of gonococcal pili and progress in the development of a gonococcal pilus vaccine for gonorrhea p. 155-178. In G. F. Brooks E. C. Gotschlich K. K. Holmes W. D. Sawyer and F. E. Young (ed.) Immunobiology of Neisseria gonorrhoeae. American Society for Microbiology Washington D.C.
2. Buchanan T. M. 1977. Surface antigens: pili p. 255-272. In R. B. Roberts (ed.) The gonococcus John Wiley & Sons Inc. New York.
3. Antigen-specific serotyping of Neisseria gonorrhoeae: characterization based upon principal outer membrane protein;Buchanan T. M.;Infect. Immun.,1981
4. Western blotting;Burnette W. N.;Anal. Biochem.,1981
5. Penicillin sensitivity and serum resistance are independent attributes of strains of Neisseria gonorrhoeae causing disseminated gonococcal infection;Eisenstein B. I.;Infect. Immun.,1977
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