Pichia acaciae Killer System: Genetic Analysis of Toxin Immunity-Reference-Cited by-同舟云学术

Pichia acaciae Killer System: Genetic Analysis of Toxin Immunity

Published:2007-07 Issue:13 Volume:73 Page:4373-4378
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Paluszynski John P.¹,Klassen Roland¹,Meinhardt Friedhelm¹

Affiliation:

1. Institut für Molekulare Mikrobiologie und Biotechnologie, Westfälische Wilhelms-Universität Münster, Corrensstr. 3, D-48149 Münster, Germany

Abstract

ABSTRACT The gene responsible for self-protection in the Pichia acaciae killer plasmid system was identified by heterologous expression in Saccharomyces cerevisiae . Resistance profiling and conditional toxin/immunity coexpression analysis revealed dose-independent protection by pPac1-2 ORF4 and intracellular interference with toxin function, suggesting toxin reinternalization in immune killer cells.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00271-07

Reference41 articles.

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