Elongation Factor P Is Important for Sporulation Initiation-Reference-Cited by-同舟云学术

Elongation Factor P Is Important for Sporulation Initiation

Published:2023-02-22 Issue:2 Volume:205 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Feaga Heather A.¹²,Hong Hye-Rim¹,Prince Cassidy R.¹,Rankin Ananda²,Buskirk Allen R.³^ORCID,Dworkin Jonathan²^ORCID

Affiliation:

1. Department of Microbiology, Cornell University, Ithaca, New York, USA

2. Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, New York, USA

3. Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Abstract

Elongation factor P (EF-P) is a universally conserved translation factor that prevents ribosome stalling at amino acids that form peptide bonds with low efficiency, particularly polyproline tracts. Phenotypes associated with EF-P deletion are pleiotropic, and the mechanistic basis underlying many of these phenotypes is unclear.

Funder

HHS | NIH | National Institute of General Medical Sciences

HHS | NIH | National Institute of Allergy and Infectious Diseases

Burroughs Wellcome Fund

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00370-22

Reference73 articles.

1. What recent ribosome structures have revealed about the mechanism of translation