Low Level of Antifungal Resistance in Iranian Isolates of Candida glabrata Recovered from Blood Samples in a Multicenter Study from 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of PDR1-Reference-Cited by-同舟云学术

Low Level of Antifungal Resistance in Iranian Isolates of Candida glabrata Recovered from Blood Samples in a Multicenter Study from 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of PDR1

Published:2019-07 Issue:7 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Arastehfar Amir¹,Daneshnia Farnaz¹,Zomorodian Kamiar²³,Najafzadeh Mohammad Javad⁴,Khodavaisy Sadegh⁵⁶,Zarrinfar Hossein⁷,Hagen Ferry¹,Zare Shahrabadi Zahra²³,Lackner Michaela⁸,Mirhendi Hossein⁹,Salehi Mohammadreza¹⁰,Roudbary Maryam¹¹,Pan Weihua¹²,Kostrzewa Markus¹³,Boekhout Teun¹¹⁴

Affiliation:

1. Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands

2. Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3. Department of Medical Mycology and Parasitology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

4. Department of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5. Zoonoses Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran

6. Department of Medical Parasitology and Mycology, Tehran University of Medical Sciences, Tehran, Iran

7. Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

8. Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria

9. Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

10. Department of Infectious Diseases and Tropical Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

11. Department of Medical Mycology and Parasitology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

12. Department of Dermatology, Shanghai Key Laboratory of Molecular Medical Mycology, Shanghai Institute of Medical Mycology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China

13. Bruker Daltonik GmbH, Bremen, Germany

14. Institute of Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, Netherlands

Abstract

Establishing an effective empirical antifungal therapy requires that national surveillance studies be conducted. Herein, we report the clinical outcome of infections with and the microbiological features of Iranian isolates of Candida glabrata derived from patients suffering from candidemia.

Funder

Marie-Sklodowska Curie

National health department of China

Shanghai Science and Technology Committee

National Natural Science Foundation of China

Second Military Medical University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02503-18